If there’s been one sure pick in the NFL over the past years, it’s this one: Seattle at home against an AFC team. The Seahawks are 4-2-1 after losing to the Saints in Week 8. However, the Seahawks are a different team when facing an AFC Team.

Since Russell Wilson’s debut in Seattle in 2012, the Seahawks are 9-0 SU and 6-3 ATS against the AFC. In all three games where the Seahawks failed to cover, the spread was in double digits. Of course the Bills will certainly have their hands full, but there’s more than one reason to visit MyBookie and take Buffalo as +7 point underdog.

The Bills have dominated the NFC West this year, going 3-0 against the division, and covering the spread in all three games.

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